Ruta graveolens commonly known as Rue, belongs to the family Rutaceae, native to the Mediterranean region and richly present all over the world. In India, it is used in Ayurveda Homeopathy and Unani medical system and also widely used in countries like China, Brazil, Ethiopia, North, Central, South America in the time immemorial, it is used as a traditional medicine. Ruta graveolens shows various therapeutic values and is useful in healing visual problem, skin problem, reproductive problem, Rheumatism, Dermatitis, pain, cold etc. It also has many peculiarities like anticancer, antitumor, antidiabetic, anti-inflammatory, cytotoxic, due to the presence of many phytochemicals such as flavonoids phenols, tennis, alkaloids, and furocoumarines etc. Ruta graveolens, is also used in commercial aspects as well as for ritual purposes.