Periodontal disease (PD) is a complex chronic inflammatory disease involving bacterial activity and resulting in destruction of the tissues that support the teeth. This study was performed to analyse the effect of periodontal disease on cardiovascular diseases.The major connection between gum disease and heart disease is that bacteria from the mouth enter the bloodstream through the gums and oral bacteria stick to fatty plaques in the bloodstream, directly contributing to blockages. Oral bacteria also trigger an inflammatory response, causing the blood vessels to swell, reducing blood flow and increasing risk of clots. From the study the major conclusions made is treatments aimed at decreasing periodontal infection and inflammation can reduce serum inflammatory biomarkers predictive of cardiovascular disease and improve vascular responses. The cardiologists are advised to educate their patients on the role of maintaining oral health for general health and to refer to the periodontist when needed. At the same time the general dentists and the periodontists are advised to keep a check on the inflammation and maintain a zero tolerance for bleeding gums to prevent the risk of percolation of bacteria to other sites in the body.