Liposome are small vesicle of spherical shape that can be produced from cholesterol, nontoxic surfactants, sphingolipids, glycolipids, long chain fatty acid and even membrane protein Almost from the time of their discovery in 1960’s and the demonstration of their entrapment potential, liposome vesicle have drawn attention of researchers as potential carriers of various bioactive molecules that could be used for therapeutic application in humans and animal. liposome solubilize lipophilic drug candidates that would otherwise be difficult to administer i.v. the encapsulated drug is inaccessible to metabolizing enzyme; conversely, body compartment such as erythrocyte and tissue injection site are not directly exposed to full dose of the drug.