An eco-friendly cloud point extraction procedure was developed using non-ionic surfactant, Triton X-114, to extract vardenafil HCl (VARD) from aqueous solution. The method was based on the extraction of vardenafil HCl and bromophenol blue from acetate buffer media pH 3.5 to surfactant rich phase (Triton X-114) and formed an-ion pair complex. The extracted surfactant-rich phase was diluted with methanol and its absorbance was measured spectrophotometrically at 420 nm. The effect of different variables such as pH, Triton X-114 concentration, cloud point temperature and time was established. The calibration graph was linear in a wide range of 0.1-2.0 µg mL-1 of vardenafil HCl with r2 =0.9996. The detection limit based on three times standard deviation of the blank (3s) was 20 ng mL-1 and relative standard deviation (R.S.D%) is 1.80. The preconcentration factor is 20. The proposed method was applied to the determination of vardenafil HCl in pharmaceutical formulations (tablets).