The present study was designated to study the antimicrobial activities and antioxidant activity of aqueous and alcohol extracts that were prepared from fresh fruits of Carica papaya, Punica granatum, Psidium guava. The antimicrobial activities of the extracts were tested against bacteria E.coil, P.aurignosa, S.aureus, B.subtiis by the use of agar well diffusion method. Antioxidant activity were tested by Reducing power assay method, Superoxide anion scavenging activity, Total antioxidant capacity.